Diabetic Foot
For Doctors - 11

Report by Dr. Arun Bal

   

Diabetes is likely to be an epidemic of the century. As per the prediction of WHO, India will have largest number of diabetic patients in the world. This number will be approximately 57 million. 15% of these patients will get food problem. 1% will lose their limbs due to diabetic food gangrene. 50% of those patients will be between the age group of 35 to 45 years. However to avoid this disaster it is necessary to understand the basic mechanism of the foot and the change which occurs in diabetes. The triad of factors which cause foot problem in diabetes are : Neuropathy, Vasculopathy and Injury. Almost all the patients have both neuropathy as well as vasculopathy. However what triggers the problem is injury. It is necessary to maintain the integrity of the epithelial barrier. If this is done then in spite of the deformity, foot remains intact. The diabetic foot injuries are missed because they are silent and it is difficult to detect these injuries with High Index of suspicion. These injuries are like ICEBERG. There are various types of injuries which trigger the problem. However
the most important injury is caused by pressure. The normal walking cycle involves various phases like Heel Strike, Mid Stance and Propulsion Phase. What keeps the foot intact and pressure distributed is the planter fascia. The characteristics of plantar fascia change in diabetes due to non enzymatic gyration and its rigidity is lost which prevents it from distribution of pressure.

In every human walking cycle the forefoot bears 600 kPa pressure. This causes significant ischemia and recovers instantly as soon as the foot goes into the next phase. However this recovery is delayed or is absent in diabetes. This causes continuous anorexia and inflammation. If the patient keeps on walking then the exudates form and lead to blister which break down and cause ulcer? The foot in diabetes changes the walking pattern and the majority of the patients have hyper pronation. The 1st MTP joint remains in the ground contact for longer time. The Limited Joint Mobility increases the pressure. These factors together cause foot ulcer. In small percentage of patients the foot supinates and the pressure and the ground contact time is more on 5th MTP Joint. In these patients the ulcer occurs on 5th MTP Joints. The impulse
loading is more important than only the pressure. Thus in the presence of advancing neuropathy if the patient keeps on walking unprotected and unmonitored then the foot starts collapsing and leads to Charcot Foot, the most dreaded complication. The 2nd MT and 2nd Cuneiform joint are the earliest joints to show the changes of destruction. Therefore regular foot check up of foot and the measurement of foot pressures to find out and protect the high pressure areas are important. These can be done with various modalities.

The infected foot needs to be treated aggressively and the debridement needs to be done on anatomical basis. The partial foot should at least be preserved as the higher amputation has very high 5 years mortality. It is safer to have deformed foot with good footwear than higher amputation with sophisticated prosthesis. The dressings of diabetic foot wounds and ulcers should be done by the material which maintains most wound environment. Also it is necessary to avoid the agents like Eusol/Salon/Hydrogen Peroxide. It is of utmost importance to maintain off loading of the affected foot till the wound heals.

Vascular lesions require proper assessment and prompt revascularization. In any patient when A/B index is less than 0.6 then immediate full vascular assessment should be done followed by proper debridement.

The footwear is the most important aspect of the diabetic foot management. The fundamental principle of the footwear in diabetes is "Foot Wear Should Do What Foot Cannot Do". Therefore the footwear has to be customized with areas of stress isolation to protect high pressure areas. It is necessary to persuade the patient to use the prescribed footwear indoor as well as outdoor.

The International Consensus in 1999 decided on St. Vincent's Declaration, which stated that the major limb amputations due to diabetes should be reduced by 50% within 5 years. If we had to achieve this objective then off loading of the affected leg/foot should have been aggressively pursued. Our country is likely to face a major epidemic in near future and only way to prevent the disaster is to install preventive strategies of foot care and footwear, which only can prevent loss of limb(s).

Diabetic Foot
This may not be far off,
'if ignored'